Module 4 :: Intro To the Lab
Topic 2 :: Laboratory Processes Used in Forensic DNA Analysis
Stochastic Effects in DNA Amplification
Sometimes forensic evidence samples contain quantities of DNA that are very small. When an analyst tries to copy the DNA using PCR, the result can be an unbalanced representation of the alleles present and in an extreme case can cause allelic dropout. This can make interpretation of the data difficult and may result in an improper reporting of the DNA profile.
Click here to view an animation on allelic dropout.