Module 4 :: Intro To the Lab
Topic 1 :: History and Development of Forensic DNA Analysis
DNA Typing—The PCR Revolution
While RFLP technology provided the ability to individualize samples to their donors, it required a large amount of biological sample and the presence of high-quality (non-degraded) DNA. RFLP testing averaged 10-12 weeks to complete.
PCR technology permitted very small samples and partially degraded DNA to be tested. It also shortened the analysis time from weeks to days. This technology is the primary reason why DNA testing is increasingly being used today as an investigative tool for law enforcement.