- 01 Introduction
- 02 Biology of DNA
- 03 Practical Issues Specific to DNA Evidence
- 04 Introduction to the Forensic DNA Laboratory
- 05 Assuring Quality in DNA Testing
- 06 Understanding a Forensic DNA Lab Report
- 07 Statistics and Population Genetics
- 08 Mitochondrial DNA & Y-STR Analysis
- 09 Forensic DNA Databases
- 10 Collection of DNA Evidence from Suspects and Arrestees
- 11 Pretrial DNA Evidence Issues
- 12 Victim Issues
- 13 Trial Presentation
- 14 Postconviction DNA Cases
- 15 Emerging Trends
Principles of Forensic DNA
for Officers of the Court
for Officers of the Court
Module 4 :: Intro To the Lab
Topic 1 :: History and Development of Forensic DNA Analysis
DNA Typing—RFLP
The process used to examine the VNTRs from a forensic sample is called restriction fragment length polymorphism (RFLP). The technique takes advantage of the fact that the DNA fragment containing the 25 copies is larger than the corresponding fragment from the other chromosome containing the 18 copies.
Analyses of the lengths of the fragments reveal that when looking at multiple VNTRs within and between individuals, no two people have the same assortment of lengths. This technique became known to the public as "DNA fingerprinting" because of its powerful ability to discriminate between unrelated individuals.
