- 01 Introduction
- 02 Biology of DNA
- 03 Practical Issues Specific to DNA Evidence
- 04 Introduction to the Forensic DNA Laboratory
- 05 Assuring Quality in DNA Testing
- 06 Understanding a Forensic DNA Lab Report
- 07 Statistics and Population Genetics
- 08 Mitochondrial DNA & Y-STR Analysis
- 09 Forensic DNA Databases
- 10 Collection of DNA Evidence from Suspects and Arrestees
- 11 Pretrial DNA Evidence Issues
- 12 Victim Issues
- 13 Trial Presentation
- 14 Postconviction DNA Cases
- 15 Emerging Trends
Principles of Forensic DNA
for Officers of the Court
for Officers of the Court
Module 8 :: mtDNA & Y-STR
Topic 4 :: Y-STR Laboratory Analysis
Indications for Y-STR Analysis (cont.)
Often the male component comprises a tiny fraction of the DNA recovered from fingernails with most of the DNA originating from the victim herself. Also, unlike mixtures of sperm and non-sperm cells, it is not possible to perform a differential extraction procedure to subfractionate and purify the DNA further into its constituent male and female components. The inability to obtain a standard (autosomal) STR profile from the male, despite the presence of male cells, is the result. However, Y chromosome analysis may yield the genetic profile of the perpetrator due to the ability of the system to ignore the overwhelming quantities of female DNA present.
