Principles of Forensic DNA
for Officers of the Court
Principles of Forensic DNA for Officers of the Court
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Module 15 :: Emerging Trends

Topic 2 :: Automation

Low Copy Number DNA Analysis

The ability to develop an STR DNA profile on items with very little DNA deposited on them, such as touched objects like a doorknob or drinking glass, is expected to aid in solving property crimes during which perpetrators have hot-wired a vehicle or stolen other property while bare-handed.

This type of analysis, called "low copy number" (LCN) DNA analysis, requires the same steps as standard STR testing but uses a higher number of PCR cycles to amplify the evidentiary DNA. The increased number of cycles produces more copies of the target DNA, making their STR typing more successful.

LCN protocols are currently in research and development stages.

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